Psychoactive

PSYCHOACTIVE

PSYCHOACTIVE aims to bind diverging scientific and academic research to understand the roles of set and setting in mental illness, create original discourse on the effects of psychedelics in human biology, behavior, and perception, and provide new and better ways think about, communicate, and use altered states of consciousness.

Can You Feel It? On Psychedelic Microdosing

[...] Microdosing, beyond the sub-perceptual, for solving currently relevant complex procedural and social-emotional problems that require innovative solutions. [...] Warning: the serotonin system is involved in regulating energy metabolism, social status (including resource access priority such as to food and mates), and psychedelics may lead to a challenging re-evaluation of priorities. [...] (Read more)

A New Understanding: The Science of Psilocybin – Summary and Critical Analysis

[...] outlines and expands on the psycho-social implications of the film [...] An original discussion about some of the science of how psychedelics work in the brain is offered–a critical feature which was largely left out of the film, possibly for its complexity. [...] (Read more)

D. W. Woolley, the Serotonin Hypothesis and the Genesis of Psychopharmacology

[...] The view that biochemistry had no stake in the brain was soon to change after a series of discoveries about serotonin in the early 1950s. [...] Psychosis and mania are characterized in part by an over-ascription of meaning, and depression with a lack of meaning, consistent with Woolley’s work on the hyper- and hypo-serotonergic effects on bipolar psychosis. (Read more)

Does Dream Content Predict Cognitive Abilities?

[...] REM dreams reflect the use of existing experience to solve cognitively challenging learning tasks requiring innovative solutions (Smith, 2012). We hypothesize that reasoning and working memory would be positively related to dream experiences of good fortune and success, and negatively related to experiences of misfortune. [...] (Read more)

Adult Disorganized Attachment: Pathology, Absorption, and Mystical Experience

[...] failed resolution of trauma, and specifically disorganized attachment, expresses itself in a propensity for mystical experiences (unrelated to religious/spiritual beliefs), mediated by trait absorption. [...] (Read more)

Multiple Functional Enhancements of Dopamine Signaling by LSD

[...] This study adds to the growing body of evidence that serotonergic psychedelics affect the dopamine system, implicating them in reward and motivation. This may partially explain anecdotal reports of psychedelics dramatically affecting those with symptoms of attention deficit. [...] (Read more)

Brief Moments in Darknet History

[...] 2011: New era of potential dawns for psychedelics as they soar through international mail. 2013 - Ross Ulbricht trialed as 'Dread Pirate Roberts,' Silk road shuts down. Soon after, Silk Road 2 opens. [...] (Read more)

Hallucinogen Persisting Perceptual Disorder – A Very Brief Summary

[...] Some factors were found predicting occurrence of HPPD, including pre-existing tinnitus, "floaters," and trouble concentrating, but most importantly, anxiety and panic reactions during the experience. This lead to speculation of hallucinogen-induced PTSD symptomatology as a useful model for HPPD. [...] (Read more)

Psychedelic Clinical Trials for Terminally Ill Patients Set to Begin at St. Vincent Hospital

[...] Confronting terminal illness can lead to a devastating sense of demoralization, loss of hope, meaning, desire for hastened death, depression, and anxiety. Terminal cancer is the second leading cause of death in the world. Cancer will take one in four of us, and almost half of us will face it—at least once, at a rate of 1.6 million people in the US alone every year.[...] (Read more)

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